Description

(2S)-2-(4-Bromo-Phenyl)-Morpholine-4-Carboxylic Acid tert-Butyl Ester is a high-purity, chiral building block of significant importance in advanced organic synthesis. Its core value lies in providing a stereochemically defined morpholine scaffold with a bromo-phenyl handle, enabling precise construction of complex molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and oncology targets.
• Agrochemical Synthesis: Used in the creation of advanced, stereoselective herbicides, fungicides, and insecticides where the specific spatial orientation of the molecule is critical for activity.
• Ligand and Catalyst Development: Serves as a precursor for designing novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology & Proteomics: Employed as a building block for synthesizing molecular probes and activity-based protein profiling (ABPP) reagents.
• Material Science Research: Potential intermediate in the synthesis of specialty polymers and advanced organic materials with specific optical or electronic properties.

Basic Information

Product Name	(2S)-2-(4-Bromo-Phenyl)-Morpholine-4-Carboxylic Acid tert-Butyl Ester
CAS No.	1131220-37-5
Molecular Formula	C15H20BrNO3
Molecular Weight	342.23 g/mol
Synonyms	tert-Butyl (2S)-2-(4-bromophenyl)morpholine-4-carboxylate; (2S)-2-(4-Bromophenyl)-4-(tert-butoxycarbonyl)morpholine; (S)-tert-Butyl 2-(4-bromophenyl)morpholine-4-carboxylate; Boc-(S)-2-(4-Bromophenyl)morpholine; (S)-2-(4-Bromophenyl)-N-Boc-morpholine; 4-Boc-2-(4-bromophenyl)morpholine, (S)-; 1131220-37-5
EINECS	Contact for details

Quality Control

Our production of (2S)-2-(4-Bromo-Phenyl)-Morpholine-4-Carboxylic Acid tert-Butyl Ester adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric purity and NMR for structural confirmation, to ensure compliance with research and development standards. A detailed Certificate of Analysis (COA) providing batch-specific data for identity, purity, and chiral excess is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.