Description

1-(2-Bromo-5-Hydroxyphenyl)Ethanone is a specialized brominated aromatic ketone building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a bromine substituent and a phenolic hydroxyl group, makes it a versatile intermediate for constructing complex molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory pathways.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators, leveraging its halogenated phenolic core.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and tags for studying biological processes and enzyme activity.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to form biaryl structures.
• Fine Chemical Manufacturing: Acts as a building block for the production of dyes, pigments, and other performance chemicals requiring specific brominated aromatic motifs.

Basic Information

Product Name	1-(2-Bromo-5-Hydroxyphenyl)Ethanone
CAS No.	1127422-81-4
Molecular Formula	C8H7BrO2
Molecular Weight	215.05 g/mol
Synonyms	2'-Bromo-5'-hydroxyacetophenone; 1-(2-Bromo-5-hydroxyphenyl)ethan-1-one; 2-Bromo-5-hydroxyacetophenone; 5-Acetyl-2-bromophenol; 2-Bromo-5-acetylphenol; Ethanone, 1-(2-bromo-5-hydroxyphenyl)-
EINECS	Contact for details

Quality Control

Our 1-(2-Bromo-5-Hydroxyphenyl)Ethanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant packaging.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.