Description

3-(6-Chloroimidazo[1,2-B]Pyridazin-2-Yl)Benzonitrile CAS NO 1125406-99-6 is a high-purity, advanced pharmaceutical intermediate belonging to the imidazopyridazine class of heterocyclic compounds. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for targeted therapies. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and development programs. The compound's specific molecular architecture makes it a key precursor for creating molecules with potential biological activity.

Application

• Pharmaceutical Intermediate: Serves as a crucial synthetic precursor in the research and development of new drug candidates, especially in oncology and central nervous system (CNS) therapeutic areas.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the multi-step synthesis of complex target molecules for preclinical and clinical studies.
• Biochemical Research: Employed as a reference standard or a probe molecule in biochemical assays to study enzyme inhibition and receptor binding.
• Medicinal Chemistry: A valuable scaffold for medicinal chemists to explore structure-activity relationships (SAR) and optimize lead compounds.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.

Basic Information

Product Name	3-(6-Chloroimidazo[1,2-B]Pyridazin-2-Yl)Benzonitrile
CAS No.	1125406-99-6
Molecular Formula	C₁₃H₇ClN₄
Molecular Weight	254.67 g/mol
Synonyms	3-(6-Chloroimidazo[1,2-b]pyridazin-2-yl)benzonitrile; 6-Chloro-2-(3-cyanophenyl)imidazo[1,2-b]pyridazine; 1125406-99-6; Benzonitrile, 3-(6-chloroimidazo[1,2-b]pyridazin-2-yl)-; 3-(6-Chloro-imidazo[1,2-b]pyridazin-2-yl)-benzonitrile; 2-(3-Cyanophenyl)-6-chloroimidazo[1,2-b]pyridazine
EINECS	Contact for details

Quality Control

Our 3-(6-Chloroimidazo[1,2-B]Pyridazin-2-Yl)Benzonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP guidelines for pharmaceutical intermediates, ensuring reliability for your critical research and development workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.