Description

2-(4-Cyanophenyl)Cyclopropane-1-Carboxylic Acid is a high-value, synthetically versatile organic building block featuring a cyclopropane ring fused to a cyanophenyl-substituted carboxylic acid. This compound matters as a critical chiral intermediate in modern pharmaceutical synthesis, enabling the construction of complex molecules with precise three-dimensional architecture. Pharmaceutical research and development organizations need it for creating novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas targeting the central nervous system and metabolic diseases.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in developing advanced pesticides and herbicides with specific stereochemical activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis.
• Material Science: A building block for advanced polymers and liquid crystalline materials.
• Academic & Industrial R&D: Employed in organic synthesis research to explore new cyclopropane-based chemical spaces.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs for client-specific molecule construction.

Basic Information

Product Name	2-(4-Cyanophenyl)Cyclopropane-1-Carboxylic Acid
CAS No.	1119807-15-6
Molecular Formula	C11H9NO2
Molecular Weight	187.20 g/mol
Synonyms	2-(4-Cyanophenyl)cyclopropanecarboxylic acid; 4-(1-Carboxycyclopropyl)benzonitrile; Cyclopropanecarboxylic acid, 2-(4-cyanophenyl)-; 2-(p-Cyanophenyl)cyclopropane-1-carboxylic acid; 1-Cyclopropane-1-carboxylic acid-4-cyanobenzene; (4-Cyanophenyl)cyclopropanecarboxylic acid; Benzonitrile, 4-(1-carboxycyclopropyl)-
EINECS	Contact for details

Quality Control

Our production of 2-(4-Cyanophenyl)Cyclopropane-1-Carboxylic Acid adheres to stringent quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.