Description

4-Iodo-3-Methoxyaniline is a versatile halogenated aniline derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both an iodine substituent and a methoxy group on the aniline ring, makes it a valuable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research institutions and chemical manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and plant growth regulators, leveraging its halogenated aniline core.
• Material Science & Dyes: Serves as a monomer or functionalizing agent in the production of specialty polymers, liquid crystals, and high-performance organic dyes and pigments.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) to form complex biaryl structures.
• Chemical Research & Development: Essential reagent in academic and industrial R&D labs for exploring new synthetic pathways and creating compound libraries.
• Ligand & Catalyst Preparation: Used to synthesize novel chelating ligands and organocatalysts for asymmetric synthesis and transition metal catalysis.

Basic Information

Item	Details
Product Name	4-Iodo-3-Methoxyaniline
CAS No.	1112840-98-8
Molecular Formula	C7H8INO
Molecular Weight	249.05 g/mol
Synonyms	3-Methoxy-4-iodoaniline; 4-Amino-2-iodoanisole; 2-Iodo-5-methoxyaniline; 4-Iodo-3-methoxybenzenamine; 1-Amino-4-iodo-2-methoxybenzene; 3-Methoxy-4-iodophenylamine; 4-Iodo-m-anisidine
EINECS	Contact for details

Quality Control

Our 4-Iodo-3-Methoxyaniline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and industrial applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as identity, assay, and impurity profiles. We are committed to supply reliability and traceability for our global B2B partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant packaging.

Specification

Item	Specification
Appearance	Light yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.