Description

Potassium 1-Boc-Pyrrole-2-Yltrifluoroborate is a high-value organoboron reagent used as a key building block in advanced organic synthesis. This compound is critical for enabling efficient cross-coupling reactions, particularly in the construction of complex heterocyclic scaffolds. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a stable, air-tolerant boronate source for coupling with aryl/heteroaryl halides to form biaryl and heterobiaryl structures.
• Pharmaceutical Intermediate Synthesis: A crucial precursor in the multi-step synthesis of drug candidates, especially those containing functionalized pyrrole cores.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that require complex heterocyclic motifs.
• Material Science: Employed in the creation of organic electronic materials, such as conductive polymers and organic light-emitting diodes (OLEDs).
• Chemical Biology & Probe Development: Facilitates the synthesis of labeled compounds and molecular probes for biological target identification and validation.
• Process Chemistry & Scale-up: Provides a reliable and scalable reagent for transitioning from laboratory-scale discovery to pilot plant and commercial manufacturing.

Basic Information

Product Name	Potassium 1-Boc-Pyrrole-2-Yltrifluoroborate
CAS No.	1111732-78-5
Molecular Formula	C9H12BF3KNO2
Molecular Weight	273.10 g/mol
Synonyms	Potassium (1-(tert-Butoxycarbonyl)-1H-pyrrol-2-yl)trifluoroborate; Potassium 1-(tert-Butoxycarbonyl)-2-pyrrolyltrifluoroborate; 1-Boc-2-pyrrolyltrifluoroborate Potassium Salt; 1-(tert-Butoxycarbonyl)-1H-pyrrole-2-boronic acid, potassium trifluoroborate salt; 1-Boc-pyrrole-2-trifluoroboronate Potassium; Potassium 1-Boc-2-pyrrolyl-BF3; Potassium 1-Boc-pyrrol-2-yl-BF3; Potassium 1-Boc-2-pyrrolyltrifluoroborane
EINECS	Contact for details

Quality Control

Our Potassium 1-Boc-Pyrrole-2-Yltrifluoroborate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system is designed to meet the stringent requirements of research and development as well as cGMP environments for non-clinical use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (argon or nitrogen) when possible to prevent decomposition. Keep the container tightly sealed in a desiccator for long-term storage.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
NMR Purity	Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.