Description

n-(4-Fluorobenzyl)-1-([1,2,4]Triazolo[4,3-B]Pyridazin-6-Yl)Piperidine-3-Carboxamide is a high-purity, non-nucleoside heterocyclic compound of significant interest in advanced pharmaceutical research and development. Its complex molecular architecture, featuring fused triazolopyridazine and piperidine rings, makes it a valuable pharmacological building block for exploring novel therapeutic pathways. This compound is primarily utilized by pharmaceutical R&D organizations and contract research organizations (CROs) engaged in the discovery of new bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical synthetic precursor in the development of new chemical entities (NCEs) for drug discovery programs.
• Biochemical Research: Used as a reference standard or a ligand in biochemical assays to study enzyme inhibition and receptor binding activities.
• Medicinal Chemistry: Acts as a core scaffold for structure-activity relationship (SAR) studies, particularly in areas targeting central nervous system (CNS) disorders or inflammatory pathways.
• Academic Research: Employed in university and institutional labs for fundamental research in heterocyclic chemistry and pharmacology.
• Preclinical Development: Utilized in the synthesis of candidate compounds for pharmacokinetic and toxicological evaluation.

Basic Information

Product Name	n-(4-Fluorobenzyl)-1-([1,2,4]Triazolo[4,3-B]Pyridazin-6-Yl)Piperidine-3-Carboxamide
CAS No.	1111400-36-2
Molecular Formula	C19H19FN6O
Molecular Weight	366.40 g/mol
Synonyms	1-([1,2,4]Triazolo[4,3-b]pyridazin-6-yl)-N-[(4-fluorophenyl)methyl]piperidine-3-carboxamide; N-[(4-Fluorophenyl)methyl]-1-[1,2,4]triazolo[4,3-b]pyridazin-6-ylpiperidine-3-carboxamide; 1-(1,2,4-Triazolo[4,3-b]pyridazin-6-yl)-N-(4-fluorobenzyl)piperidine-3-carboxamide; UNII-2S0K8QK5QN; 2S0K8QK5QN; CHEMBL3186668; BDBM50121271; AKOS009158966
EINECS	Contact for details

Quality Control

Our n-(4-Fluorobenzyl)-1-([1,2,4]Triazolo[4,3-B]Pyridazin-6-Yl)Piperidine-3-Carboxamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, essential for research integrity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with ICH guidelines for impurities and can provide material suitable for use under GMP conditions for preclinical studies upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.