Description

4-(1-Methylethyl)-2-(Tributylstannyl)-Thiazole is a specialized organotin-thiazole hybrid compound, representing a high-value building block in advanced synthetic chemistry. Its core value lies in its dual functionality, combining the reactivity of a stannane with the heterocyclic framework of a thiazole, enabling precise cross-coupling and functionalization reactions. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries developing novel active ingredients and functional polymers.

Application

• As a key organotin reagent in Stille cross-coupling reactions for constructing complex C-C bonds in pharmaceutical intermediates.
• As a versatile synthetic building block for the development of novel thiazole-containing drug candidates and agrochemicals.
• In materials science research for the synthesis of functionalized polymers and advanced organic electronic materials.
• For the derivatization and labeling of bioactive molecules in medicinal chemistry programs.
• As a precursor in catalytic systems and ligand design for transition metal catalysis.
• In academic and industrial R&D for exploring new synthetic methodologies involving organometallic chemistry.

Basic Information

Product Name	4-(1-Methylethyl)-2-(Tributylstannyl)-Thiazole
CAS No.	1108659-24-0
Molecular Formula	C16H31NSSn
Molecular Weight	388.19 g/mol
Synonyms	2-(Tributylstannyl)-4-isopropylthiazole; 4-Isopropyl-2-(tributylstannyl)thiazole; Tributyl(4-isopropyl-2-thiazolyl)stannane; 4-(1-Methylethyl)-2-(tributylstannyl)-thiazole; 4-Isopropyl-2-tributylstannylthiazole; Stannane, tributyl(4-(1-methylethyl)-2-thiazolyl)-; (4-Isopropyl-2-thiazolyl)tributyltin
EINECS	Contact for details

Quality Control

Our production of 4-(1-Methylethyl)-2-(Tributylstannyl)-Thiazole adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. Each lot is characterized by advanced analytical techniques including NMR, HPLC, and GC to verify identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC/GC)	≥95.0%
Tin (Sn) Content	30.0 - 31.0 %
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.