Description

1-(Bromomethyl)-2-(4-Methylphenyl)Benzene is a specialized brominated aromatic compound that serves as a versatile and critical building block in advanced organic synthesis. Its molecular structure, featuring both a reactive benzyl bromide moiety and a biaryl system, makes it an essential intermediate for constructing complex molecules. This high-purity intermediate is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting CNS and oncology.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and fungicides, leveraging its biaryl structure for bioactive molecule design.
• Ligand and Catalyst Precursor: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the creation of organic electronic materials, such as hole-transport materials or monomers for conjugated polymers.
• Chemical Biology Probes: Utilized to create molecular probes and tags for studying biological systems and protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs serving the global life sciences market.

Basic Information

Product Name	1-(Bromomethyl)-2-(4-Methylphenyl)Benzene
CAS No.	1108187-28-5
Molecular Formula	C14H13Br
Molecular Weight	261.16 g/mol
Synonyms	2-(4-Methylphenyl)benzyl Bromide; 1-(Bromomethyl)-2-(p-Tolyl)benzene; [1,1'-Biphenyl]-2-methyl, 4'-methyl-α-bromo-; α-Bromo-2-(4-methylphenyl)toluene; 2-(p-Tolyl)benzyl Bromide; 4'-Methyl[1,1'-biphenyl]-2-ylmethyl Bromide; (2-(4-Methylphenyl)phenyl)methyl Bromide
EINECS	Contact for details

Quality Control

Our 1-(Bromomethyl)-2-(4-Methylphenyl)Benzene is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable and ensure compliance with relevant global regulatory frameworks for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.