Description

4-Methyl-1-Phenyl-1H-Pyrazolo[3,4-D]Pyridazine-7-Thiol is a high-purity, heterocyclic organic compound with the CAS number 1105198-16-0, serving as a critical advanced intermediate in modern chemical synthesis. Its unique fused pyrazolo-pyridazine scaffold with a reactive thiol group makes it a valuable building block for constructing complex molecular architectures. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting kinase inhibition or other enzyme-related pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging its heterocyclic core for bioactivity.
• Material Science: Serves as a building block for organic semiconductors, ligands for catalysis, or functional polymers due to its electron-rich structure.
• Chemical Biology & Proteomics: The thiol group allows for site-specific conjugation, making it useful for probe development and bioconjugation strategies.
• Academic & Contract Research: Employed in fundamental organic chemistry research and by CROs (Contract Research Organizations) for custom synthesis projects.

Basic Information

Product Name	4-Methyl-1-Phenyl-1H-Pyrazolo[3,4-D]Pyridazine-7-Thiol
CAS No.	1105198-16-0
Molecular Formula	C₁₃H₁₀N₄S
Molecular Weight	254.31 g/mol
Synonyms	4-Methyl-1-phenyl-1H-pyrazolo[3,4-d]pyridazine-7-thiol; 1H-Pyrazolo[3,4-d]pyridazine-7-thiol, 4-methyl-1-phenyl-; 1105198-16-0; 4-Methyl-1-phenylpyrazolo[3,4-d]pyridazine-7-thiol; 7-Mercapto-4-methyl-1-phenyl-1H-pyrazolo[3,4-d]pyridazine
EINECS	Contact for details

Quality Control

Every batch of 4-Methyl-1-Phenyl-1H-Pyrazolo[3,4-D]Pyridazine-7-Thiol is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its sensitivity to oxidation, it is recommended to handle and store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.