Description

1-(4-Fluorophenyl)-4-Methoxy-6-Oxo-1,6-Dihydropyridazine-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its distinct pyridazine carboxylic acid core structure. This compound is of significant commercial importance for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the multi-step synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities with improved efficacy and safety profiles.
• Process Development & Scale-Up: Employed in pilot plant and commercial-scale manufacturing to establish robust and cost-effective synthetic routes for target APIs.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting the pharmaceutical industry's outsourced drug discovery and production needs.
• Academic Research: Utilized in university and institutional labs for fundamental studies in heterocyclic chemistry and the development of new synthetic methodologies.

Basic Information

Item	Detail
Product Name	1-(4-Fluorophenyl)-4-Methoxy-6-Oxo-1,6-Dihydropyridazine-3-Carboxylic Acid
CAS No.	1105193-26-7
Molecular Formula	C13H11FN2O4
Molecular Weight	278.24 g/mol
Synonyms	4-Methoxy-1-(4-fluorophenyl)-6-oxo-1,6-dihydropyridazine-3-carboxylic acid; 1-(4-Fluorophenyl)-4-methoxy-6-oxo-1,6-dihydropyridine-3-carboxylic acid (common misnomer); 4-Methoxy-1-(p-fluorophenyl)-6-oxo-1,6-dihydropyridazine-3-carboxylic acid; 1105193-26-7; 1-(4-Fluorophenyl)-4-methoxy-6-oxo-1,6-dihydropyridazine-3-carboxylate; Fluorophenyl Methoxy Oxo Dihydropyridazine Carboxylic Acid
EINECS	Contact for details

Quality Control

Our production of 1-(4-Fluorophenyl)-4-Methoxy-6-Oxo-1,6-Dihydropyridazine-3-Carboxylic Acid adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the exacting standards required for pharmaceutical R&D and manufacturing. A Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. For long-term storage, consider conditions under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.