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2-Pyrrolidin-1-Yl-7-(2-Thienyl)[1,3]Thiazolo[4,5-D]Pyridazin-4(5H)-One CAS NO 1105192-70-8


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CAS No.:1105192-70-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-Pyrrolidin-1-Yl-7-(2-Thienyl)[1,3]Thiazolo[4,5-D]Pyridazin-4(5H)-One is a high-value, heterocyclic organic compound featuring a complex fused-ring structure. This molecule serves as a critical pharmacological intermediate and scaffold in modern drug discovery programs. It is primarily sought after by research and development teams in the pharmaceutical and biotechnology sectors for the synthesis of novel active pharmaceutical ingredients (APIs) targeting a range of therapeutic areas.

Application

  • Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and oncology targets.
  • Kinase Inhibitor Research: Serves as a core scaffold for the development of potent and selective kinase inhibitors due to its privileged heterocyclic structure.
  • Medicinal Chemistry & Lead Optimization: Used extensively in structure-activity relationship (SAR) studies to optimize potency, selectivity, and pharmacokinetic properties of lead compounds.
  • Chemical Biology Probes: Employed in the creation of tool compounds for studying specific biological pathways and target validation.
  • Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client-sponsored drug discovery projects.
  • Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and new therapeutic modalities.

Basic Information

Item Details
Product Name 2-Pyrrolidin-1-Yl-7-(2-Thienyl)[1,3]Thiazolo[4,5-D]Pyridazin-4(5H)-One
CAS No. 1105192-70-8
Molecular Formula C15H14N4OS2
Molecular Weight 330.43 g/mol
Synonyms 7-(Thiophen-2-yl)-2-(pyrrolidin-1-yl)[1,3]thiazolo[4,5-d]pyridazin-4(5H)-one; 2-(Pyrrolidin-1-yl)-7-(thiophen-2-yl)thiazolo[4,5-d]pyridazin-4(5H)-one; 1105192-70-8; Thiazolopyridazinone derivative; Pyrrolidinyl thienyl thiazolopyridazinone
EINECS Contact for details

Quality Control

Every batch of 2-Pyrrolidin-1-Yl-7-(2-Thienyl)[1,3]Thiazolo[4,5-D]Pyridazin-4(5H)-One is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the exacting standards required for research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are supplied with each shipment. Our quality protocols are designed to support regulatory filings and ensure batch-to-batch consistency for critical pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item Specification
Appearance Off-white to light yellow solid
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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