Description

3-Amino-n-tert-Butylpropanamide Hydrochloride is a high-purity, protected amino acid derivative used as a critical building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring a stable, salt-form intermediate with a sterically hindered tert-butyl protecting group. It is primarily utilized in the development of novel pharmaceuticals, agrochemicals, and sophisticated peptide mimetics where precise molecular architecture is paramount.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for peptide-based drugs and enzyme inhibitors.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and plant growth regulators that require specific chiral centers and protected functional groups.
• Peptidomimetic Research: Serves as a crucial component for constructing non-natural amino acid residues in peptides to enhance metabolic stability and bioavailability.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds and molecular probes for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, specialized intermediates.
• Academic & Industrial R&D: A valuable reagent for method development and exploratory chemistry in university laboratories and corporate R&D centers.

Basic Information

Product Name	3-Amino-n-tert-Butylpropanamide Hydrochloride
CAS No.	1103861-54-6
Molecular Formula	C7H17N2O·HCl
Molecular Weight	180.68 g/mol (Free base: 145.22 g/mol)
Synonyms	3-Amino-N-(tert-butyl)propanamide Hydrochloride; 3-Amino-N-tert-butylpropanamide HCl; tert-Butyl 3-aminopropanamide Hydrochloride; 3-Aminopropanamide, N-(1,1-dimethylethyl)-, hydrochloride; Propanamide, 3-amino-N-(1,1-dimethylethyl)-, hydrochloride; 1103861-54-6; ATBPA HCl
EINECS	Contact for details

Quality Control

Every batch of 3-Amino-n-tert-Butylpropanamide Hydrochloride is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.