Description

Morpholine (3As,5R,6S,6As)-6-Hydroxy-2,2-Dimethyltetrahydrofuro[2,3-D][1,3]Dioxole-5-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its specific stereochemistry. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in chiral drug development where precise molecular configuration is paramount. It serves as a key building block for research and production in the pharmaceutical and fine chemical industries, enabling the creation of targeted therapeutics.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon in the multi-step synthesis of novel APIs, especially for antiviral, anticancer, and neurological drugs.
• Chiral Catalyst & Ligand Precursor: Used in the development and preparation of asymmetric catalysts for stereoselective chemical reactions.
• Organic Synthesis Building Block: Employed in complex organic transformations, including cyclization and functional group manipulations, for research-scale molecule development.
• Process Chemistry: Utilized in route scouting and optimization for the scalable manufacturing of high-value fine chemicals.
• Academic & Industrial R&D: Serves as a reference standard and starting material in medicinal chemistry and process research laboratories.

Basic Information

Product Name	Morpholine (3As,5R,6S,6As)-6-Hydroxy-2,2-Dimethyltetrahydrofuro[2,3-D][1,3]Dioxole-5-Carboxylate
CAS No.	1103738-20-0
Molecular Formula	C12H19NO7
Molecular Weight	289.28 g/mol
Synonyms	(3aR,5R,6S,6aR)-6-Hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxole-5-carboxylic acid morpholine salt; Morpholine salt of (3aR,5R,6S,6aR)-6-Hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxole-5-carboxylic acid; Isopropylidene-L-ascorbic acid morpholine salt; L-Ascorbic acid derivative morpholine salt
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency for critical R&D and scale-up processes. Quality is verified through comprehensive analytical methods including HPLC, chiral analysis, NMR, and mass spectrometry to confirm identity, purity, and stereochemical integrity. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.