Description

Leucine, n-[(3-Methylphenyl)Sulfonyl]- is a specialized sulfonamide derivative of the essential amino acid L-leucine, identified by CAS NO 1102899-58-0. This compound serves as a crucial high-purity building block and key intermediate in advanced organic synthesis, particularly for pharmaceutical research and development. It is primarily utilized by R&D chemists and process development teams in the life sciences sector seeking to develop novel therapeutic agents and bioactive molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly protease inhibitors and other targeted therapies.
• Peptidomimetics Research: Used to construct modified peptide backbones for studying protein-protein interactions and developing stable bioactive analogs.
• Chemical Biology Probes: Serves as a building block for creating activity-based probes and labeled compounds for enzyme mechanism studies.
• Agrochemical Development: Potential intermediate in the research and synthesis of new generation herbicides or plant growth regulators.
• Material Science: Can be incorporated into specialized polymers or coatings to impart specific functional properties.

Basic Information

Product Name	Leucine, n-[(3-Methylphenyl)Sulfonyl]-
CAS No.	1102899-58-0
Molecular Formula	C13H19NO4S
Molecular Weight	285.36 g/mol
Synonyms	N-(3-Methylphenyl)sulfonylleucine; N-Tosylleucine (meta-methyl derivative); m-Toluenesulfonylleucine; Leucine, N-[(3-methylphenyl)sulfonyl]-; 2-Amino-4-methylpentanoic acid, N-[(3-methylphenyl)sulfonyl]-; (S)-2-((3-Methylphenyl)sulfonamido)-4-methylpentanoic acid; 1102899-58-0; N-(m-Tolylsulfonyl)-L-leucine
EINECS	Contact for details

Quality Control

Our Leucine, n-[(3-Methylphenyl)Sulfonyl]- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing including HPLC for purity, chiral analysis, and identity confirmation to ensure it meets the exacting standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.