Description

4-Bromo-2-Fluoro-Benzamidine is a high-purity, halogenated benzamidine derivative that serves as a critical building block in modern organic synthesis. This compound is valued for its unique molecular structure, which enables the introduction of both bromine and fluorine substituents into complex target molecules, facilitating the development of novel compounds with tailored properties. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of protease inhibitors and other small-molecule drug candidates, particularly those targeting specific enzyme families.
• Agrochemical Research: Used in the development of new herbicides and pesticides, where the fluorine and bromine atoms can enhance biological activity and environmental stability.
• Chemical Biology Probe Synthesis: Employed in creating activity-based probes and molecular tools for studying enzyme function and protein interactions in biological systems.
• Material Science: Acts as a monomer or cross-linking agent in the development of specialty polymers and advanced functional materials.
• Organic Synthesis Building Block: Provides a versatile handle for further functionalization via the amidine group, enabling palladium-catalyzed cross-coupling reactions and other transformations.

Basic Information

Product Name	4-Bromo-2-Fluoro-Benzamidine
CAS No.	1100752-71-3
Molecular Formula	C7H6BrFN2
Molecular Weight	217.04 g/mol
Synonyms	4-Bromo-2-fluorobenzamidine; 2-Fluoro-4-bromobenzamidine; Benzenecarboximidamide, 4-bromo-2-fluoro-; 4-Bromo-2-fluoro-benzenecarboximidamide; 4-Bromo-2-fluorophenylformamidine; (4-Bromo-2-fluorophenyl)methanimidamide; 1100752-71-3 (CAS)
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Fluoro-Benzamidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment. We adhere to cGMP principles for the production of materials intended for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light sources to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.