Description

9R-10Alpha-Hydroxyepigambogic Acid is a bioactive, oxidized derivative of gambogic acid, a natural compound with significant research interest. This specific stereoisomer is valued for its potential as a high-purity reference standard and a key intermediate in pharmaceutical research and development. It is primarily sought by research institutions and pharmaceutical companies engaged in the discovery of novel therapeutic agents, particularly in the fields of oncology and anti-inflammatory drug development.

Application

• Pharmaceutical Reference Standard: Serves as a certified analytical standard for quality control and method validation in drug discovery pipelines.
• Bioactive Compound Research: Used in in vitro and in vivo studies to investigate mechanisms of action related to apoptosis and cell cycle regulation.
• Medicinal Chemistry Intermediate: Acts as a crucial building block for the semi-synthesis of novel gambogic acid analogs with optimized pharmacokinetic properties.
• Biochemical Pathway Analysis: Employed in studies targeting specific enzymes and signaling pathways involved in cancer and inflammation.
• High-Value Fine Chemical Synthesis: Utilized in the production of specialized compounds for preclinical and clinical trial materials.

Basic Information

Product Name	9R-10Alpha-Hydroxyepigambogic Acid
CAS No.	1097882-33-1
Molecular Formula	C38H44O9
Molecular Weight	668.75 g/mol
Synonyms	9R-10α-Hydroxyepigambogic Acid; (9R,10α)-10-Hydroxy-9,10-dihydrogambogic Acid; 10α-Hydroxy-9R-epigambogic Acid; 9R,10α-Dihydroxy-9,10-dihydrogambogic Acid (related); Epigambogic Acid 10α-ol; Gambogic Acid Derivative
EINECS	Contact for details

Quality Control

Our 9R-10Alpha-Hydroxyepigambogic Acid is produced under a strict quality management system to ensure batch-to-batch consistency and high purity, suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant guidelines for analytical reference materials to support your critical research and development work.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. This compound is light-sensitive and should be handled under appropriate conditions to prevent degradation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.