Description

Methyl 1-Amino-2,3-Dihydro-1H-Indene-5-Carboxylate is a high-purity, functionalized indane derivative serving as a critical chiral building block and advanced pharmaceutical intermediate. Its unique fused-ring structure with both amino and ester functionalities makes it a versatile synthon for constructing complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates targeting central nervous system (CNS) disorders, cardiovascular diseases, and metabolic conditions.
• Chiral Building Block: Utilized in asymmetric synthesis to introduce the 1-amino-2,3-dihydro-1H-indene scaffold, which is a privileged structure in medicinal chemistry.
• Agrochemical Research: Serves as a starting material for developing new herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Used to create novel chiral ligands for transition metal catalysis and organocatalysts for enantioselective transformations.
• Material Science Precursor: Potential monomer or functional additive in the development of specialty polymers and advanced organic materials.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and the exploration of new chemical space.

Basic Information

Product Name	Methyl 1-Amino-2,3-Dihydro-1H-Indene-5-Carboxylate
CAS No.	1097196-76-3
Molecular Formula	C11H13NO2
Molecular Weight	191.23 g/mol
Synonyms	1-Amino-2,3-dihydro-1H-indene-5-carboxylic acid methyl ester; Methyl 1-aminoindane-5-carboxylate; 5-(Methoxycarbonyl)-2,3-dihydro-1H-inden-1-amine; 1-Amino-2,3-dihydro-1H-indene-5-carboxylic acid, methyl ester; 1097196-76-3; 5-Carbomethoxy-1-aminoindane
EINECS	Contact for details

Quality Control

Every batch of Methyl 1-Amino-2,3-Dihydro-1H-Indene-5-Carboxylate is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.