Description

(3R,4S)-4-Aminotetrahydro-2H-Pyran-3-Ol Hydrochloride is a high-purity chiral building block and pharmaceutical intermediate. This compound is valued for its defined stereochemistry, which is critical for synthesizing active pharmaceutical ingredients (APIs) with specific biological activity. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for the development of novel therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug molecules, particularly those targeting neurological and infectious diseases.
• Agrochemical Research: Used in the development of new pesticides and herbicides with enhanced efficacy and selectivity.
• Asymmetric Catalysis: Serves as a precursor or ligand in catalytic systems for stereoselective chemical transformations.
• Peptidomimetics & Bioactive Molecules: Incorporated into the backbone of peptide analogs and other bioactive compounds to modulate stability and receptor interaction.
• Academic & Process Chemistry: Utilized in research laboratories for method development and scale-up studies in organic synthesis.
• Custom Synthesis: A starting material for the contract manufacturing of proprietary compounds and advanced intermediates.

Basic Information

Product Name	(3R,4S)-4-Aminotetrahydro-2H-Pyran-3-Ol Hydrochloride
CAS No.	1096594-11-4
Molecular Formula	C5H12ClNO2
Molecular Weight	153.61 g/mol
Synonyms	(3R,4S)-4-Aminooxane-3-ol hydrochloride; 4-Amino-3-hydroxytetrahydro-2H-pyran hydrochloride; (3R,4S)-3-Hydroxy-4-aminotetrahydropyran hydrochloride; 1096594-11-4; 4-Aminotetrahydro-2H-pyran-3-ol hydrochloride, (3R,4S)-; UNII-9K5P8V6K5F; SCHEMBL21806227; AKOS040759977
EINECS	Contact for details

Quality Control

Our (3R,4S)-4-Aminotetrahydro-2H-Pyran-3-Ol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and stereochemical purity compliant with research and cGMP starting material standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and residual solvent content is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere to maintain stability and purity. Keep the container tightly sealed in a desiccated environment when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% de
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.