Description

n-[(9R)-6'-Methoxycinchonan-9-Yl]-3,5-Bis(Trifluoromethyl)-Benzenesulfonamide is a high-purity, chiral organocatalyst derived from cinchona alkaloid architecture. This compound matters for its critical role in facilitating asymmetric synthesis, enabling the production of enantiomerically pure intermediates essential for advanced pharmaceuticals. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-performance catalysts for complex synthetic routes.

Application

• Asymmetric Organocatalysis: Employed as a privileged catalyst for a variety of enantioselective carbon-carbon and carbon-heteroatom bond-forming reactions.
• Pharmaceutical Intermediate Synthesis: Key for the scalable production of chiral active pharmaceutical ingredients (APIs) and advanced drug candidates.
• Methodology Development: A valuable tool for academic and industrial research in developing new catalytic asymmetric transformations.
• Fine Chemical Manufacturing: Used in the synthesis of high-value, enantiopure specialty chemicals and fragrances.
• Agrochemical Research: Applied in the development of chiral pesticides and herbicides with improved efficacy and environmental profiles.

Basic Information

Product Name	n-[(9R)-6'-Methoxycinchonan-9-Yl]-3,5-Bis(Trifluoromethyl)-Benzenesulfonamide
CAS No.	1096403-83-6
Molecular Formula	C₂₉H₂₆F₆N₂O₃S
Molecular Weight	596.59 g/mol
Synonyms	(9R)-N-[3,5-Bis(trifluoromethyl)phenyl]-6'-methoxycinchonan-9-sulfonamide; (R)-3,5-Bis(trifluoromethyl)-N-(6'-methoxycinchonan-9-yl)benzenesulfonamide; (R)-N-[3,5-Bis(trifluoromethyl)phenyl]-6'-methoxycinchonan-9-sulfonamide; Cinchona Alkaloid-Derived Sulfonamide Catalyst; (9R)-DHQD 3,5-DiTFBS; Asymmetric Phase-Transfer Catalyst (PTC); Chiral Benzenesulfonamide Organocatalyst
EINECS	Contact for details

Quality Control

Our n-[(9R)-6'-Methoxycinchonan-9-Yl]-3,5-Bis(Trifluoromethyl)-Benzenesulfonamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high chiral purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and enantiomeric excess. We adhere to relevant standards for research and process chemistry applications, ensuring material integrity for critical synthetic work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.