Description

3-Bromo-5-Fluorobenzyl Chloride is a versatile and highly reactive halogenated benzyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic positioning of halogen atoms, which allows for selective functionalization and the construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require a reliable, high-purity intermediate for developing new active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the fluorine and bromine substituents for enhanced bioactivity and environmental stability.
• Liquid Crystal & OLED Material Production: Serves as a building block for creating fluorinated and brominated aromatic cores essential in electronic display and lighting technologies.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Ligand & Catalyst Development: Employed in the preparation of specialized phosphine or nitrogen-based ligands for asymmetric catalysis.
• Polymer Modification: Used to introduce halogenated benzyl groups into polymer chains to alter physical properties like flame retardancy and refractive index.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and process chemistry research in both academic and industrial settings.

Basic Information

Product Name	3-Bromo-5-Fluorobenzyl Chloride
CAS No.	1094651-50-9
Molecular Formula	C7H5BrClF
Molecular Weight	223.47 g/mol
Synonyms	1-(Bromomethyl)-3-fluoro-5-chlorobenzene; (3-Bromo-5-fluorophenyl)methyl chloride; 3-Bromo-5-fluorobenzylchloride; α-Chloro-3-bromo-5-fluorotoluene; 3-Bromo-5-fluoro-benzyl chloride; 5-Fluoro-3-bromobenzyl chloride; Benzene, 1-(bromomethyl)-3-fluoro-5-chloro-; 3-Fluoro-5-bromobenzyl chloride
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-5-Fluorobenzyl Chloride is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for sensitive synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. Due to its reactivity, it should be handled and stored under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.