Description

1-(Azetidin-1-Yl)-3-Chloropropan-1-One is a specialized organic building block featuring an azetidine ring and a reactive chloropropanone moiety. This compound is valued for its role as a key intermediate in the synthesis of complex pharmacologically active molecules, particularly in medicinal chemistry research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel heterocyclic scaffolds and targeted libraries.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly those targeting neurological disorders and metabolic diseases.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) around the azetidine pharmacophore.
• Agrochemical Synthesis: Serves as a precursor in the development of new herbicides and fungicides with novel modes of action.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A key starting material for CDMOs (Contract Development and Manufacturing Organizations) producing APIs (Active Pharmaceutical Ingredients) for clinical trials.
• Academic Research: Employed in university and institutional labs for methodological development in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	1-(Azetidin-1-Yl)-3-Chloropropan-1-One
CAS No.	1094428-17-7
Molecular Formula	C6H10ClNO
Molecular Weight	147.60 g/mol
Synonyms	3-Chloro-1-(azetidin-1-yl)propan-1-one; 1-Azetidinyl 3-chloropropyl ketone; 3-Chloro-1-(azetidin-1-yl)-1-propanone; 1-(Azetidin-1-yl)-3-chloro-1-propanone; 3-Chloropropan-1-one, 1-(azetidin-1-yl)-; Azetidine, 1-(3-chloro-1-oxopropyl)-; 1094428-17-7 (CAS)
EINECS	Contact for details

Quality Control

Our 1-(Azetidin-1-Yl)-3-Chloropropan-1-One is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or development specifications. Our quality commitment supports applications requiring high-purity chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.