Description

6-Chloro-7-(Chloromethyl)-2,3-Dihydrobenzo[B][1,4]Dioxine is a specialized organic compound belonging to the benzodioxine class, characterized by its two chlorine substituents which make it a valuable and reactive synthetic intermediate. This compound matters for its role as a key building block in the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing complex heterocyclic architectures.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, or insecticides, where the benzodioxine core can contribute to biological activity.
• Ligand and Catalyst Development: Acts as a starting material for creating specialized ligands used in asymmetric catalysis or metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials, dyes, or polymers where the chloromethyl group offers a site for further functionalization.
• Custom Synthesis and Contract Manufacturing: A key raw material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Item	Detail
Product Name	6-Chloro-7-(Chloromethyl)-2,3-Dihydrobenzo[B][1,4]Dioxine
CAS No.	1094400-29-9
Molecular Formula	C9H8Cl2O2
Molecular Weight	219.06 g/mol
Synonyms	6-Chloro-7-(chloromethyl)-2,3-dihydro-1,4-benzodioxine; 2,3-Dihydrobenzo[1,4]dioxine, 6-chloro-7-(chloromethyl)-; 6-Chloro-7-chloromethyl-2,3-dihydro-1,4-benzodioxin; 1,4-Benzodioxine, 6-chloro-7-(chloromethyl)-2,3-dihydro-; 6,7-Dichloromethyl-2,3-dihydro-1,4-benzodioxine (incorrect but common misnomer); BDD-CMCl (abbreviation); Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our 6-Chloro-7-(Chloromethyl)-2,3-Dihydrobenzo[B][1,4]Dioxine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.