Description

6-Chloro-3-(4-Fluorophenyl)[1,2,4]Triazolo[4,3-B]Pyridazine is a high-value, heterocyclic organic compound featuring a fused triazolopyridazine core, which is of significant interest in advanced pharmaceutical research and development. Its molecular architecture, incorporating both chloro and fluorophenyl substituents, makes it a versatile and critical building block for medicinal chemistry. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the development of novel drug candidates, particularly those targeting kinase inhibition.
• Medicinal Chemistry Research: Used extensively in structure-activity relationship (SAR) studies and lead optimization programs due to its privileged heterocyclic scaffold.
• Agrochemical Development: Acts as a potential intermediate in the synthesis of new herbicides and pesticides, leveraging its bioactive heterocyclic structure.
• Material Science Research: Investigated as a building block for organic electronic materials and advanced polymers, given its conjugated system.
• Biochemical Tool Compound: Utilized in biochemical assays and as a reference standard for studying specific biological pathways and enzyme interactions.

Basic Information

Item	Details
Product Name	6-Chloro-3-(4-Fluorophenyl)[1,2,4]Triazolo[4,3-B]Pyridazine
CAS No.	1094260-22-6
Molecular Formula	C12H6ClFN4
Molecular Weight	260.66 g/mol
Synonyms	6-Chloro-3-(4-fluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazine; 6-Chloro-3-(p-fluorophenyl)-s-triazolo[4,3-b]pyridazine; 1094260-22-6; 6-Chloro-3-(4-fluorophenyl)-1,2,4-triazolo[4,3-b]pyridazine; 3-(4-Fluorophenyl)-6-chloro-1,2,4-triazolo[4,3-b]pyridazine; 6-Chloro-3-(4-fluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazine
EINECS	Contact for details

Quality Control

Our 6-Chloro-3-(4-Fluorophenyl)[1,2,4]Triazolo[4,3-B]Pyridazine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, essential for sensitive research applications. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profile.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.