Description

(5-Chloro-2-(Difluoromethoxy)Phenyl)Methanamine is a high-purity, specialized aromatic amine building block designed for advanced chemical synthesis. This compound matters for its role as a critical intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its unique halogenated difluoromethoxy structure enables precise molecular modifications. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce specific functional groups into complex molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, leveraging its halogenated structure for bioactivity.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of advanced polymers and functional materials with specific electronic or surface properties.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up services for clients requiring bespoke chemical entities.

Basic Information

Product Name	(5-Chloro-2-(Difluoromethoxy)Phenyl)Methanamine
CAS No.	1094236-98-2
Molecular Formula	C8H8ClF2NO
Molecular Weight	207.60 g/mol
Synonyms	1-(5-Chloro-2-(difluoromethoxy)phenyl)methanamine; 5-Chloro-2-(difluoromethoxy)benzylamine; (5-Chloro-2-(difluoromethoxy)phenyl)methylamine; 2-(Difluoromethoxy)-5-chlorobenzylamine; α-Amino-5-chloro-2-(difluoromethoxy)toluene; Benzenemethanamine, 5-chloro-2-(difluoromethoxy)-; 1094236-98-2; 5-Chloro-α-(difluoromethoxy)benzylamine
EINECS	Contact for details

Quality Control

Our (5-Chloro-2-(Difluoromethoxy)Phenyl)Methanamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.