Description

5-[(4-Methylphenyl)Sulfonyl]-3-Oxopentanoic Acid Ethyl Ester is a high-purity sulfonyl ketoester building block of significant interest in advanced organic synthesis. This compound matters as a versatile intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly those containing sulfonamide or β-ketoester pharmacophores.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators requiring specific sulfonyl-based active centers.
• Organic Synthesis Building Block: Serves as a versatile precursor for Michael additions, Claisen condensations, and other C-C bond-forming reactions in complex molecule assembly.
• Material Science Precursor: Potential use in the synthesis of specialized polymers or organic electronic materials where the sulfonyl and ketoester groups impart specific electronic properties.
• Chemical Biology Probe Development: Utilized in creating tool compounds and molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	5-[(4-Methylphenyl)Sulfonyl]-3-Oxopentanoic Acid Ethyl Ester
CAS No.	1093348-62-9
Molecular Formula	C15H20O5S
Molecular Weight	312.38 g/mol
Synonyms	Ethyl 5-[(4-Methylphenyl)sulfonyl]-3-oxopentanoate; Ethyl 3-Oxo-5-(p-tolylsulfonyl)pentanoate; 5-(p-Tolylsulfonyl)-3-oxopentanoic Acid Ethyl Ester; 3-Oxo-5-(4-methylphenylsulfonyl)pentanoic Acid Ethyl Ester; TOPS-Et Ester; p-Tolylsulfonyl Pentanedioic Acid Monoethyl Ester β-Ketoester
EINECS	Contact for details

Quality Control

Our 5-[(4-Methylphenyl)Sulfonyl]-3-Oxopentanoic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.