Description

8-Bromo-6-Fluorochroman-4-One is a high-purity fluorinated and brominated chromanone derivative, serving as a critical advanced intermediate in modern organic synthesis. Its unique halogenated structure makes it a valuable building block for constructing complex molecules with tailored properties. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the research and development of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the preparation of advanced intermediates for next-generation herbicides and fungicides, leveraging the bioactivity of the halogenated chromanone core.
• Material Science Research: Acts as a precursor for synthesizing specialized organic compounds used in organic light-emitting diodes (OLEDs) and other functional materials.
• Chemical Biology Probes: Serves as a scaffold for developing molecular probes to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific halogenated heterocycles.

Basic Information

Product Name	8-Bromo-6-Fluorochroman-4-One
CAS No.	1092350-87-2
Molecular Formula	C9H6BrFO2
Molecular Weight	245.05 g/mol
Synonyms	8-Bromo-6-fluoro-4-chromanone; 6-Fluoro-8-bromochroman-4-one; 4H-1-Benzopyran-4-one, 8-bromo-6-fluoro-2,3-dihydro-; 2,3-Dihydro-8-bromo-6-fluoro-4H-1-benzopyran-4-one
EINECS	Contact for details

Quality Control

Our 8-Bromo-6-Fluorochroman-4-One is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing including HPLC, NMR, and GC-MS to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.