Description

6,7-Difluorochroman-4-One is a high-purity fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for developing novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular modification. Pharmaceutical R&D departments and fine chemical manufacturers need it for constructing complex molecules where the difluorinated chromanone scaffold imparts desirable metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, especially in central nervous system (CNS) and anti-inflammatory research.
• Agrochemical Research: Used in developing advanced pesticides and herbicides where the fluorinated structure enhances biological activity and environmental persistence.
• Material Science Precursor: Serves as a monomer or precursor for synthesizing specialized polymers and organic electronic materials.
• Fluorine Chemistry Studies: Employed in academic and industrial research to study the effects of fluorine substitution on chemical reactivity and physical properties.
• Ligand and Catalyst Development: Utilized to create novel chiral ligands and organocatalysts for asymmetric synthesis.
• Dye and Pigment Intermediate: Acts as a starting material for synthesizing fluorinated chromophores with unique optical properties.

Basic Information

Product Name	6,7-Difluorochroman-4-One
CAS No.	1092349-93-3
Molecular Formula	C9H6F2O2
Molecular Weight	184.14 g/mol
Synonyms	4H-1-Benzopyran-4-one, 6,7-difluoro-2,3-dihydro-; 6,7-Difluoro-2,3-dihydro-4H-chromen-4-one; 6,7-Difluoro-3,4-dihydro-2H-chromen-4-one; 6,7-Difluorochroman-4-one; 2,3-Dihydro-6,7-difluoro-4H-chromen-4-one; Chroman-4-one, 6,7-difluoro-
EINECS	Contact for details

Quality Control

Our 6,7-Difluorochroman-4-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.