Description

1-Amino-3-(2,2,2-trifluoroethyl)thiourea is a specialized organofluorine thiourea derivative, a high-value building block prized for its unique trifluoroethylamine moiety. This compound is critical for introducing fluorine-containing pharmacophores into target molecules, significantly altering their physicochemical and biological properties. It is primarily utilized by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the research and development of fluorinated drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in creating advanced fluorinated pesticides and herbicides, where the trifluoromethyl group enhances lipophilicity and metabolic stability.
• Material Science Research: Serves as a precursor for novel fluorinated polymers or ligands with specific electronic or surface properties.
• Chemical Biology Probes: Employed in the synthesis of activity-based probes or inhibitors to study enzyme mechanisms involving sulfur or fluorine chemistry.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring precise incorporation of a trifluoroethyl-thiourea functional group.

Basic Information

Product Name	1-Amino-3-(2,2,2-trifluoroethyl)thiourea
CAS No.	1092300-87-2
Molecular Formula	C3H6F3N3S
Molecular Weight	173.16 g/mol
Synonyms	N-(Amino)-N'-(2,2,2-trifluoroethyl)thiourea; 1-Amino-3-(2,2,2-trifluoroethyl)-2-thiourea; (2,2,2-Trifluoroethyl)thiourea, 1-amino-; 2,2,2-Trifluoroethyl-1-aminothiourea; Thiourea, N-amino-N'-(2,2,2-trifluoroethyl)-; 1-Amino-3-(trifluoroethyl)thiourea; N-Amino-N'-(2,2,2-trifluoroethyl)thiourea
EINECS	Contact for details

Quality Control

Our 1-Amino-3-(2,2,2-trifluoroethyl)thiourea is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for advanced chemical synthesis. A detailed Certificate of Analysis (COA) providing purity by HPLC, identity confirmation by NMR and IR spectroscopy, and impurity profiles is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong acids, strong bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.