Description

tert-Butyl(2,2,2-Trifluoroethyl)Amine is a specialized organofluorine amine building block of significant interest in advanced chemical synthesis. Its molecular structure, featuring both a sterically hindered tert-butyl group and a trifluoroethyl moiety, makes it a valuable precursor for introducing fluorinated amine functionalities. This compound is primarily utilized by research and development chemists and process engineers in the pharmaceutical and agrochemical sectors. It serves as a key intermediate in the development of novel active ingredients, where its unique properties can influence bioavailability and metabolic stability.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of fluorinated drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides where the fluorine atoms enhance biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of fluorinated polymers, surfactants, and specialty materials with unique surface properties.
• Chemical Biology Probes: Useful for incorporating fluorine tags into molecules for studies using techniques like 19F NMR spectroscopy.

Basic Information

Product Name	tert-Butyl(2,2,2-Trifluoroethyl)Amine
CAS No.	1092294-10-4
Molecular Formula	C6H12F3N
Molecular Weight	155.16 g/mol
Synonyms	N-(2,2,2-Trifluoroethyl)-2-methyl-2-propanamine; 2,2,2-Trifluoro-N-(1,1-dimethylethyl)ethanamine; 1,1-Dimethylethyl(2,2,2-trifluoroethyl)amine; N-tert-Butyl-2,2,2-trifluoroethylamine; 2-Methyl-2-(2,2,2-trifluoroethylamino)propane; t-Butyl(2,2,2-trifluoroethyl)amine; (2,2,2-Trifluoroethyl)(tert-butyl)amine
EINECS	Contact for details

Quality Control

Our tert-Butyl(2,2,2-Trifluoroethyl)Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong acids and strong oxidizing agents. Due to its fluoride/strong alkali nature, ensure containers are kept tightly sealed to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.