Description

3-Bromo-6-(tert-Butyl)Pyridazine is a high-purity, functionalized heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the strategic combination of a bromine substituent, a versatile handle for cross-coupling reactions, and a bulky tert-butyl group, which can impart desirable steric and electronic properties to target molecules. This compound is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the construction of complex pyridazine-based scaffolds in drug discovery and crop protection agent development.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting kinase inhibitors and other biologically relevant heterocycles.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, where the pyridazine core is a common pharmacophore.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis, leveraging the bromine atom for functionalization.
• Material Science: Employed in the synthesis of organic electronic materials, such as charge-transport layers or light-emitting components, where its structural motifs can tune electronic properties.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client R&D.

Basic Information

Product Name	3-Bromo-6-(tert-Butyl)Pyridazine
CAS No.	1086383-74-5
Molecular Formula	C8H11BrN2
Molecular Weight	215.09 g/mol
Synonyms	3-Bromo-6-tert-butylpyridazine; 6-tert-Butyl-3-bromopyridazine; tert-Butyl 3-bromopyridazine; Pyridazine, 3-bromo-6-(1,1-dimethylethyl)-; 1086383-74-5; 3-Bromo-6-(1,1-dimethylethyl)pyridazine
EINECS	Contact for details

Quality Control

Our 3-Bromo-6-(tert-Butyl)Pyridazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.