Description

1-(5-Bromopyridin-3-Ylsulfonyl)Piperidin-4-Ol is a high-purity, advanced pharmaceutical intermediate featuring a bromopyridine and piperidine sulfonamide scaffold. This compound is valued for its role as a critical building block in medicinal chemistry, enabling the synthesis of novel bioactive molecules. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of small molecule drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel therapeutic agents.
• Kinase Inhibitor Development: Serves as a core scaffold for the design and synthesis of potential kinase inhibitors.
• Chemical Biology Probes: Utilized in the creation of tool compounds for studying biological targets and mechanisms.
• Custom Synthesis: Employed in contract research and manufacturing (CRO/CMO) for bespoke chemical synthesis projects.
• Library Synthesis: A valuable component for generating diverse compound libraries for high-throughput screening.

Basic Information

Product Name	1-(5-Bromopyridin-3-Ylsulfonyl)Piperidin-4-Ol
CAS No.	1086064-87-0
Molecular Formula	C10H13BrN2O3S
Molecular Weight	321.19 g/mol
Synonyms	4-Piperidinol, 1-[(5-bromo-3-pyridinyl)sulfonyl]-; 1-[(5-Bromopyridin-3-yl)sulfonyl]piperidin-4-ol; 1-(5-Bromo-3-pyridinesulfonyl)-4-hydroxypiperidine; 4-Hydroxy-1-(5-bromopyridine-3-sulfonyl)piperidine; 1-(5-Bromopyridin-3-Ylsulfonyl)Piperidin-4-Ol; 1086064-87-0
EINECS	Contact for details

Quality Control

Our 1-(5-Bromopyridin-3-Ylsulfonyl)Piperidin-4-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider the use of desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.