Description

trans-(1S,2S)-Methyl 3-Aminocyclopentanecarboxylate Hydrochlorid is a high-purity, stereochemically defined chiral building block essential for advanced pharmaceutical synthesis. Its value lies in providing a rigid, functionalized cyclopentane scaffold that is critical for constructing complex molecules with specific three-dimensional architectures. This compound is primarily needed by research and development chemists and process scale-up teams in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and antiviral therapies.
• Agrochemical Research: Used in the development of enantiomerically pure pesticides and herbicides where specific stereochemistry impacts biological activity.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing chiral ligands and organocatalysts.
• Peptidomimetics & Conformationally Restricted Analogs: Incorporated into peptide backbones to induce specific turns and enhance metabolic stability.
• Academic & Contract Research: Utilized in medicinal chemistry programs for exploring structure-activity relationships (SAR).
• Custom Synthesis & Scale-Up: Supplied for custom manufacturing projects requiring multi-kilogram quantities under cGMP guidelines.

Basic Information

Product Name	trans-(1S,2S)-Methyl 3-Aminocyclopentanecarboxylate Hydrochlorid
CAS No.	1085842-51-8
Molecular Formula	C7H14ClNO2
Molecular Weight	179.65 g/mol
Synonyms	Methyl (1S,2S)-3-aminocyclopentanecarboxylate hydrochloride; (1S,2S)-Methyl 3-aminocyclopentanecarboxylate HCl; trans-Methyl 3-aminocyclopentanecarboxylate hydrochloride; Methyl trans-3-aminocyclopentanecarboxylate hydrochloride; (1S,2S)-3-(Methoxycarbonyl)cyclopentylamine hydrochloride; Cyclopentanecarboxylic acid, 3-amino-, methyl ester, hydrochloride, (1S,2S)-rel-; (1S,2S)-rel-Methyl 3-aminocyclopentanecarboxylate hydrochloride
EINECS	Contact for details

Quality Control

Our trans-(1S,2S)-Methyl 3-Aminocyclopentanecarboxylate Hydrochlorid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) and standard pharmacopeial identification and purity tests, to ensure compliance with industry standards. Certificates of Analysis (COA) with full traceability are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Enantiomeric Excess (Chiral HPLC)	≥99.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.