Description

4-(3-Amino-Phenyl)-Morpholin-3-One is a high-purity, specialized organic intermediate featuring a unique molecular architecture combining an aromatic amine with a morpholinone moiety. This compound is of significant value in advanced pharmaceutical and agrochemical research and development, serving as a critical building block for synthesizing novel active ingredients. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecules with potential biological activity.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound libraries.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its amine functionality for molecular diversification.
• Fine Chemical Building Block: Employed in custom synthesis and contract manufacturing for creating specialty chemicals, dyes, and functional materials.
• Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and hit-to-lead optimization.
• Ligand and Catalyst Precursor: The amino and carbonyl groups make it a potential precursor for chelating ligands or organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	4-(3-Amino-Phenyl)-Morpholin-3-One
CAS No.	1082495-22-4
Molecular Formula	C10H12N2O2
Molecular Weight	192.22 g/mol
Synonyms	3-(3-Aminophenyl)morpholin-2-one; 4-(3-Aminophenyl)-3-morpholinone; 3-Amino-α-(morpholino)benzenemethanol; 4-(3-Aminophenyl)morpholin-3-one; 2-Morpholinone, 4-(3-aminophenyl)-; 4-(3-Aminophenyl)-2-morpholinone; 4-(m-Aminophenyl)-3-morpholinone
EINECS	Contact for details

Quality Control

Our 4-(3-Amino-Phenyl)-Morpholin-3-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed batch-specific results are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.