Description

n-[3-(Propan-2-Yloxy)Propyl]-3-(Trifluoromethyl)[1,2,4]Triazolo[4,3-B]Pyridazin-6-Amine is a high-purity, advanced pharmaceutical intermediate featuring a unique triazolopyridazine core functionalized with a trifluoromethyl group and an isopropoxypropyl amine side chain. This compound is critical for the research and development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular interactions. It is primarily utilized by pharmaceutical R&D teams, agrochemical innovators, and specialty chemical manufacturers seeking to incorporate its specific heterocyclic scaffold into new molecular entities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in oncology, CNS disorders, and anti-inflammatory therapies.
• Agrochemical Research: Used in the development of new generation herbicides, fungicides, and plant growth regulators leveraging its heterocyclic structure.
• Chemical Biology Probe: Serves as a scaffold for designing molecular probes to study enzyme inhibition and protein-ligand interactions in biochemical research.
• Material Science Precursor: Potential intermediate for synthesizing specialty polymers or organic electronic materials with specific optoelectronic properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	n-[3-(Propan-2-Yloxy)Propyl]-3-(Trifluoromethyl)[1,2,4]Triazolo[4,3-B]Pyridazin-6-Amine
CAS No.	1081142-08-6
Molecular Formula	C13H16F3N5O
Molecular Weight	315.30 g/mol
Synonyms	6-[[3-(Isopropoxy)propyl]amino]-3-(trifluoromethyl)[1,2,4]triazolo[4,3-b]pyridazine; 3-(Trifluoromethyl)-6-[[3-(1-methylethoxy)propyl]amino]-[1,2,4]triazolo[4,3-b]pyridazine; 1081142-08-6; n-[3-(Isopropoxy)propyl]-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-amine; 3-(Trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-amine, N-[3-[(1-methylethoxy)propyl]-; UNII-6V9H3U7Q5I
EINECS	Contact for details

Quality Control

Our n-[3-(Propan-2-Yloxy)Propyl]-3-(Trifluoromethyl)[1,2,4]Triazolo[4,3-B]Pyridazin-6-Amine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis by GC, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with full traceability are provided for each lot, and we support compliance with relevant regulatory frameworks for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.