Description

cis-Quaternary Acid CAS NO 1075727-04-6 is a specialized organic compound featuring a quaternary ammonium structure with a cis-configuration, which is critical for its biological and chemical activity. This structural precision makes it a valuable intermediate for synthesizing advanced materials and active pharmaceutical ingredients (APIs) where stereochemistry is paramount. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel compounds with enhanced efficacy.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of chiral active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system or as antimicrobial agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the cis-configuration can influence biological activity and selectivity.
• Phase-Transfer Catalyst (PTC): Functions as an efficient catalyst in organic synthesis reactions, facilitating reactions between reagents in immiscible phases.
• Surfactant & Detergent Formulation: Serves as a precursor for cationic surfactants used in fabric softeners, hair conditioners, and industrial cleaning agents.
• Polymer Modification: Employed to introduce quaternary ammonium groups into polymers, enhancing properties like antimicrobial activity, dye affinity, or conductivity.
• Biochemical Research: Utilized as a tool compound or a standard in analytical research to study enzyme inhibition, membrane interactions, and other biochemical processes.

Basic Information

Product Name	cis-Quaternary Acid
CAS No.	1075727-04-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	(1R,2S)-1,2,3,4-Tetrahydro-1,2,3,4-tetramethylisoquinolin-2-ium-6-carboxylic acid; cis-1,2,3,4-Tetrahydro-1,2,3,4-tetramethylisoquinoline-6-carboxylic acid; cis-Tetramethyltetrahydroisoquinolinecarboxylic acid; cis-THIQ-6-COOH; cis-Quaternary Ammonium Acid; (1R,2S)-Tetramethyl-THIQ-6-carboxylic acid
EINECS	Contact for details

Quality Control

Our cis-Quaternary Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral chromatography to confirm the cis-configuration. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided to ensure compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% cis-isomer
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.