Description

4-Bromo-6-(Trifluoromethyl)Pyridazin-3(2H)-One is a high-value, multi-functional heterocyclic building block essential for advanced chemical synthesis. Its core value lies in the strategic combination of a bromine substituent and a trifluoromethyl group on the pyridazinone scaffold, offering versatile sites for further functionalization and introducing desirable physicochemical properties. This compound is critically needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the discovery and scale-up of novel active ingredients. Its unique structure makes it a key intermediate for creating compounds with potential biological activity.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the research and development of new drug candidates, particularly for kinase inhibitors, antiviral agents, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group can enhance bioavailability and metabolic stability.
• Material Science Research: Acts as a precursor for the synthesis of specialized ligands, organic semiconductors, or fluorinated polymers with unique electronic properties.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes, activity-based probes (ABPs), or tagged compounds for studying biological pathways.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	4-Bromo-6-(Trifluoromethyl)Pyridazin-3(2H)-One
CAS No.	1073525-70-8
Molecular Formula	C5H2BrF3N2O
Molecular Weight	242.98 g/mol
Synonyms	4-Bromo-6-(trifluoromethyl)-2,3-dihydropyridazin-3-one; 4-Bromo-6-(trifluoromethyl)-3(2H)-pyridazinone; 3(2H)-Pyridazinone, 4-bromo-6-(trifluoromethyl)-; 4-Bromo-6-trifluoromethylpyridazin-3(2H)-one; 6-(Trifluoromethyl)-4-bromopyridazin-3(2H)-one; 4-Bromo-6-(trifluoromethyl)-1,2-dihydropyridazine-3-one; BRFMPO (common abbreviation)
EINECS	Contact for details

Quality Control

Our 4-Bromo-6-(Trifluoromethyl)Pyridazin-3(2H)-One is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.