Description

Potassium (2-Fluoro-3-Isopropoxyphenyl)Trifluoroborate is a high-purity organotrifluoroborate salt, a crucial building block in modern synthetic chemistry. Its value lies in its exceptional stability and reactivity as a key coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient synthesis of complex biaryl structures. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing fluorinated biphenyl or heterobiaryl motifs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the introduction of specific fluorinated aromatic systems is required.
• Material Science Research: Serves as a building block for creating novel organic electronic materials, liquid crystals, and advanced polymers through palladium-catalyzed cross-coupling.
• Suzuki-Miyaura Cross-Coupling Reactions: Functions as a stable, air- and moisture-tolerant boronic acid equivalent for the reliable formation of carbon-carbon bonds under mild conditions.
• Library Synthesis for Drug Discovery: Enables high-throughput parallel synthesis of diverse compound libraries for screening in medicinal chemistry and hit-to-lead optimization programs.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands and organometallic catalysts used in asymmetric synthesis.

Basic Information

Product Name	Potassium (2-Fluoro-3-Isopropoxyphenyl)Trifluoroborate
CAS No.	1073468-36-6
Molecular Formula	C9H11BF4KO
Molecular Weight	252.09 g/mol
Synonyms	Potassium (2-Fluoro-3-isopropoxyphenyl)trifluoroborate; Potassium 2-Fluoro-3-isopropoxyphenyltrifluoroborate; (2-Fluoro-3-isopropoxyphenyl)trifluoroborate Potassium Salt; 2-Fluoro-3-isopropoxyphenyltrifluoroboric Acid Potassium Salt; Potassium 3-Isopropoxy-2-fluorophenyltrifluoroborate; Borate(1-), trifluoro(2-fluoro-3-isopropoxyphenyl)-, potassium; Potassium Trifluoro(2-fluoro-3-isopropoxyphenyl)borate
EINECS	Contact for details

Quality Control

Our Potassium (2-Fluoro-3-Isopropoxyphenyl)Trifluoroborate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (1H, 13C, 19F, 11B) and HPLC analysis, to ensure high chemical purity and consistent performance in sensitive cross-coupling applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (argon or nitrogen) for long-term storage or when opening the container to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
11B NMR Purity	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.