Description

Potassium 5-Methylpyridine-2-Trifluoroborate is a versatile organotrifluoroborate salt, a crucial class of reagents in modern synthetic chemistry. Its primary value lies in its exceptional stability and reactivity, serving as a superior alternative to traditional boronic acids in cross-coupling reactions. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries, where it is used to construct complex molecular architectures with high efficiency and selectivity.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key building block for the synthesis of biaryl and heterobiaryl structures prevalent in active pharmaceutical ingredients (APIs).
• Pharmaceutical Intermediate Synthesis: Used in the research and development of novel drug candidates, particularly in medicinal chemistry for lead optimization.
• Agrochemical Manufacturing: Employed in the synthesis of advanced herbicides, fungicides, and insecticides that require specific pyridine-based scaffolds.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organometallic catalysts.
• Material Science Research: Utilized in the development of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Biology Probes: Acts as a handle for bioconjugation and the synthesis of molecular probes for biological target identification.

Basic Information

Product Name	Potassium 5-Methylpyridine-2-Trifluoroborate
CAS No.	1073468-31-1
Molecular Formula	C6H6BF3KN
Molecular Weight	208.03 g/mol
Synonyms	Potassium (5-Methylpyridin-2-yl)trifluoroborate; 5-Methyl-2-pyridyltrifluoroborate Potassium Salt; 2-(5-Methylpyridyl)trifluoroboronic Acid Potassium Salt; Potassium Trifluoro(5-methylpyridin-2-yl)borate; 5-Methyl-2-pyridinyltrifluoroborate Potassium; Potassium 5-Methyl-2-pyridyltrifluoroborate; 5-Methylpyridine-2-trifluoroboronic Acid Potassium Salt
EINECS	Contact for details

Quality Control

Our Potassium 5-Methylpyridine-2-Trifluoroborate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (1H, 11B, 19F) and HPLC analysis, to ensure high purity and batch-to-batch consistency suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (argon or nitrogen) to prevent decomposition. Keep away from strong acids and strong oxidizers.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
11B NMR Purity	≥ 95.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.