Description

(R)-Tetrahydrofuran-3-Amine Hydrochloride is a high-purity chiral amine building block essential for asymmetric synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals, where stereochemical purity is critical. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the production of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Catalyst and Ligand Preparation: Serves as a precursor for chiral catalysts and ligands used in asymmetric hydrogenation and other enantioselective transformations.
• Peptidomimetics Research: Incorporated into peptide backbones to create conformationally restricted analogs with enhanced biological stability.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis and medicinal chemistry.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals requiring high optical purity.

Basic Information

Product Name	(R)-Tetrahydrofuran-3-Amine Hydrochloride
CAS No.	1072015-52-1
Molecular Formula	C₄H₁₀ClNO
Molecular Weight	123.58 g/mol
Synonyms	(R)-3-Aminotetrahydrofuran Hydrochloride; (3R)-3-Aminotetrahydrofuran Hydrochloride; (R)-Tetrahydro-3-furanamine Hydrochloride; (R)-3-Furanamine, tetrahydro-, hydrochloride; (R)-Aminotetrahydrofuran HCl; (R)-THF-3-Amine HCl; (R)-3-THF-Amine Hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-Tetrahydrofuran-3-Amine Hydrochloride is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for pharmaceutical development. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.