Description

4-(4-Amino-Phenylamino)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate featuring a protected amine and a piperidine core. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) where precise molecular architecture and functional group protection are required. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of drug candidates targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Serves as a precursor for developing novel pesticides and herbicides with specific biological activity.
• Chemical Synthesis: Used in organic chemistry research for constructing complex nitrogen-containing heterocycles and for amine protection/deprotection strategies.
• API Development: Integral in the research and scale-up phases of new Active Pharmaceutical Ingredient (API) manufacturing processes.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific molecule development.

Basic Information

Product Name	4-(4-Amino-Phenylamino)-Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	1071932-29-0
Molecular Formula	C16H25N3O2
Molecular Weight	291.39 g/mol
Synonyms	1-Boc-4-(4-aminophenylamino)piperidine; tert-Butyl 4-[(4-aminophenyl)amino]piperidine-1-carboxylate; 4-(4-Aminoanilino)piperidine-1-carboxylic acid tert-butyl ester; N-Boc-4-(4-aminophenylamino)piperidine; 1-(tert-Butoxycarbonyl)-4-[(4-aminophenyl)amino]piperidine; 4-[(4-Aminophenyl)amino]-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; 1071932-29-0; BOC-4-(4-Amino-anilino)-piperidine
EINECS	Contact for details

Quality Control

Our 4-(4-Amino-Phenylamino)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). Keep the container sealed under an inert atmosphere such as nitrogen or argon to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.