Description

cis-3-(Methoxymethyl)Cyclobutan-1-Amine is a specialized chiral amine building block featuring a cyclobutane ring system. This compound is valued for its unique structural rigidity and functional handles, making it a critical intermediate in advanced organic synthesis. It is primarily sought after by pharmaceutical and agrochemical R&D teams for the development of novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and antiviral therapeutic areas.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides where the cyclobutane scaffold can impart favorable biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to control stereochemistry.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced materials requiring rigid, functionalized cyclic components.
• Chemical Biology Probes: Utilized as a building block for creating molecular probes and tools to study biological systems and enzyme mechanisms.

Basic Information

Product Name	cis-3-(Methoxymethyl)Cyclobutan-1-Amine
CAS No.	1068704-31-3
Molecular Formula	C6H13NO
Molecular Weight	115.17 g/mol
Synonyms	cis-3-(Methoxymethyl)cyclobutanamine; (1s,3s)-3-(Methoxymethyl)cyclobutan-1-amine; 3-(Methoxymethyl)cyclobutan-1-amine (cis-); Cyclobutanamine, 3-(methoxymethyl)-, cis-; 1-Amino-3-(methoxymethyl)cyclobutane (cis-); (1R,3R)-3-(Methoxymethyl)cyclobutan-1-amine (enantiomer); 1068704-31-3
EINECS	Contact for details

Quality Control

Our cis-3-(Methoxymethyl)Cyclobutan-1-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity and impurity profiling, to ensure it meets the stringent requirements for research and process development. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Recommended long-term storage at 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.