Description

1-Bromo-4-Chloro-5-Fluoro-2-Methylbenzene is a high-purity halogenated aromatic building block essential for advanced organic synthesis. This compound is valued for its unique substitution pattern, which enables precise molecular modifications in complex chemical architectures. It is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting complex small molecules.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where its halogenated structure contributes to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the creation of novel organic electronic materials, liquid crystals, and polymers with specific optoelectronic properties.
• Chemical Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	1-Bromo-4-Chloro-5-Fluoro-2-Methylbenzene
CAS No.	1067882-53-4
Molecular Formula	C7H5BrClF
Molecular Weight	223.47 g/mol
Synonyms	4-Chloro-5-fluoro-2-methyl-1-bromobenzene; 2-Bromo-5-chloro-4-fluorotoluene; 1-Bromo-4-chloro-5-fluoro-2-methyl-benzene; 5-Fluoro-4-chloro-2-methylbromobenzene; 2-Methyl-4-chloro-5-fluorobromobenzene; Toluene, 2-bromo-5-chloro-4-fluoro-; Benzene, 1-bromo-4-chloro-5-fluoro-2-methyl-
EINECS	Contact for details

Quality Control

Our 1-Bromo-4-Chloro-5-Fluoro-2-Methylbenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.