Description

1-(4-Bromo-3-(Trifluoromethyl)Phenylsulfonyl)Piperidine is a high-purity, advanced pharmaceutical intermediate characterized by its distinct sulfonyl piperidine scaffold and halogenated aromatic ring. This compound is of significant value for medicinal chemistry research and development, particularly in the synthesis of novel bioactive molecules targeting various disease pathways. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its modifiable bromo and trifluoromethyl groups.
• Agrochemical Synthesis: Serves as a precursor in the development of new-generation pesticides and herbicides.
• Chemical Biology Probes: Utilized in the design of chemical probes for studying enzyme function and protein-protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical component for custom synthesis projects requiring high-fidelity, complex heterocyclic structures.

Basic Information

Product Name	1-(4-Bromo-3-(Trifluoromethyl)Phenylsulfonyl)Piperidine
CAS No.	1065074-37-4
Molecular Formula	C12H13BrF3NO2S
Molecular Weight	372.20 g/mol
Synonyms	1-[(4-Bromo-3-(trifluoromethyl)phenyl)sulfonyl]piperidine; Piperidine, 1-[[4-bromo-3-(trifluoromethyl)phenyl]sulfonyl]-; 4-Bromo-3-trifluoromethylbenzenesulfonylpiperidine; 1-(4-Bromo-3-trifluoromethylbenzenesulfonyl)piperidine; 1065074-37-4; CAS 1065074-37-4
EINECS	Contact for details

Quality Control

Our production of 1-(4-Bromo-3-(Trifluoromethyl)Phenylsulfonyl)Piperidine adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. All materials are supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to validate specifications, ensuring the material meets the exacting standards required for pharmaceutical intermediate use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases. The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.