Description

Potassium Cyclobutyltrifluoroborate is an organoboron reagent of significant importance in modern synthetic chemistry. Its primary value lies in its role as a stable, crystalline, and air-tolerant source of the cyclobutyl group, facilitating critical carbon-carbon bond-forming reactions. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable building blocks for complex molecule synthesis. Potassium Cyclobutyltrifluoroborate CAS NO 1065010-88-9 enables efficient and selective transformations that are difficult to achieve with other organometallic species.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for palladium-catalyzed coupling with aryl or vinyl halides to introduce the cyclobutyl moiety into complex molecular architectures.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of active pharmaceutical ingredients (APIs), particularly for creating strained ring systems that can modulate biological activity.
• Agrochemical Compound Development: Employed in the synthesis of novel herbicides, fungicides, and insecticides where the cyclobutyl ring can enhance potency and environmental profile.
• Material Science Research: Serves as a precursor for creating organic electronic materials, liquid crystals, or polymers with specific structural and electronic properties.
• Methodology Development in Academia: A valuable tool for chemists developing new catalytic cycles or exploring novel reaction pathways involving organoboron chemistry.
• Scale-up Process Chemistry: Its stability makes it suitable for transitioning from laboratory-scale discovery to pilot plant and manufacturing-scale production of target molecules.

Basic Information

Product Name	Potassium Cyclobutyltrifluoroborate
CAS No.	1065010-88-9
Molecular Formula	C4H7BF3K
Molecular Weight	161.01 g/mol
Synonyms	Potassium Cyclobutyl-Trifluoro-Borate; Cyclobutyltrifluoroboronic Acid Potassium Salt; Potassium (Cyclobutyl)trifluoroborate; Cyclobutyl-BF3K; Potassium Cyclobutyltrifluoroboranuide; Cyclobutyl Potassium Trifluoroborate; K-OCP (Cyclobutyl); Potassium Trifluoro(Cyclobutyl)Borate
EINECS	Contact for details

Quality Control

Our Potassium Cyclobutyltrifluoroborate is manufactured under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including NMR (1H, 11B, 13C, 19F) and HPLC to confirm identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment. We support compliance with cGMP and ICH guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (argon or nitrogen) to prevent decomposition. Keep away from strong acids and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (NMR / HPLC)	≥ 95%
Water Content (KF)	≤ 1.0 %
Residual Solvents (GC)	Meets ICH limits
Potassium Content (ICP)	22.0 - 26.0 %
Boron Content (ICP)	6.0 - 7.5 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.