Description

3-(4-Fluorophenyl)Tetrahydro-3-Furancarbonitrile (Saltdata: Free) is a high-purity, advanced pharmaceutical intermediate characterized by its unique furan-carbonitrile scaffold with a fluorophenyl substituent. This compound is of significant commercial value as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and metabolic disorders. It is primarily sought after by R&D laboratories, custom synthesis providers, and large-scale pharmaceutical manufacturers engaged in innovative drug development programs. The availability of this intermediate in a salt-free form offers greater flexibility for downstream synthetic modifications and precise formulation control.

Application

• Pharmaceutical Intermediate: A key synthon for the research and production of new chemical entities (NCEs) and potential drug candidates.
• Agrochemical Research: Used in the development of novel herbicides and pesticides, leveraging the bioactivity of the fluorinated aromatic system.
• Material Science Precursor: Serves as a monomer or functional additive in the synthesis of specialized polymers and advanced organic materials.
• Academic & Contract Research: Employed in university and CRO settings for methodological studies in organic synthesis and fluorine chemistry.
• Ligand & Catalyst Development: The nitrile and ether functionalities make it a candidate for constructing complex ligands in catalytic systems.

Basic Information

Product Name	3-(4-Fluorophenyl)Tetrahydro-3-Furancarbonitrile (Saltdata: Free)
CAS No.	1060817-36-8
Molecular Formula	C11H10FNO
Molecular Weight	191.20 g/mol
Synonyms	3-(4-Fluorophenyl)tetrahydrofuran-3-carbonitrile; Tetrahydro-3-(4-fluorophenyl)-3-furancarbonitrile; 3-(p-Fluorophenyl)tetrahydro-3-furancarbonitrile; 3-Cyano-3-(4-fluorophenyl)tetrahydrofuran; 1060817-36-8; 3-(4-Fluorophenyl)oxolane-3-carbonitrile
EINECS	Contact for details

Quality Control

Our production of 3-(4-Fluorophenyl)Tetrahydro-3-Furancarbonitrile (Saltdata: Free) adheres to stringent quality management protocols. Each batch is manufactured under controlled conditions and undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications. Our quality system is designed to support applications requiring high standards, including cGMP for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.