Description

m-Peg9-Ms is a high-purity, monodisperse polyethylene glycol (PEG) derivative featuring a methanesulfonate (mesylate) reactive group at one terminus. This bifunctional linker is critical for creating stable, hydrophilic conjugates in advanced pharmaceutical and biotechnological applications. It is primarily utilized by researchers and manufacturers in the fields of bioconjugation, drug delivery system development, and proteomics to modify peptides, proteins, and other bioactive molecules, enhancing their solubility and pharmacokinetic properties.

Application

• Bioconjugation Reagent: Used for the site-specific PEGylation of peptides, proteins, and antibodies to improve stability, reduce immunogenicity, and prolong circulation half-life.
• Linker Chemistry: Serves as a hydrophilic spacer in the synthesis of antibody-drug conjugates (ADCs) and other targeted therapeutic constructs.
• Polymer Chemistry: Acts as a macroinitiator or functional monomer for synthesizing well-defined, functionalized PEG-based block copolymers and hydrogels.
• Surface Modification: Employed to functionalize nanoparticles, quantum dots, and other material surfaces with hydrophilic PEG layers to enhance biocompatibility and reduce non-specific binding.
• Proteomics Research: Utilized as a tool for labeling and cross-linking biomolecules in structural and interaction studies.
• Diagnostic Reagents: Incorporated into the design of contrast agents and diagnostic probes for improved aqueous solubility and targeting.

Basic Information

Product Name	m-Peg9-Ms
CAS No.	1059588-19-0
Molecular Formula	C₂₀H₄₂O₁₂S
Molecular Weight	506.6 g/mol
Synonyms	Methoxy-PEG9-mesylate; α-Methoxy-ω-mesyl-pentaethylene glycol; 2,5,8,11,14,17,20,23,26-Nonaoxaoctacosan-28-yl methanesulfonate; mPEG9-OMs; Monomethoxy nonaethylene glycol mesylate; PEG9 monomethyl ether mesylate; 1-(Methanesulfonyl)-ω-methoxynona(ethylene oxide); m-PEG9-Ms Ester
EINECS	Contact for details

Quality Control

Our m-Peg9-Ms is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for research and pharmaceutical-grade applications. A Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Assay	≥ 90%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.