Description

4-(Trifluoromethyl)-1H-Pyrazol-5-Amine is a high-value, fluorinated pyrazole derivative serving as a critical building block in advanced organic synthesis. Its core value lies in the trifluoromethyl group, which imparts unique physicochemical properties essential for developing molecules with enhanced metabolic stability, lipophilicity, and bioavailability. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the discovery and synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the CF₃ group improves biological activity and environmental persistence.
• Material Science Research: Serves as a precursor for functionalized ligands and monomers in the development of specialty polymers and advanced materials.
• Chemical Biology: Employed as a probe or building block in the synthesis of chemical tools for studying biological pathways.
• Organic Electronics: Investigated as a component for electron-transport materials or as a modifying group in molecular design for OLEDs and other electronic applications.

Basic Information

Product Name	4-(Trifluoromethyl)-1H-Pyrazol-5-Amine
CAS No.	1056139-87-7
Molecular Formula	C₄H₄F₃N₃
Molecular Weight	151.09 g/mol
Synonyms	5-Amino-4-(trifluoromethyl)-1H-pyrazole; 4-(Trifluoromethyl)-1H-pyrazol-5-amine; 5-Amino-4-(trifluoromethyl)pyrazole; 1H-Pyrazol-5-amine, 4-(trifluoromethyl)-; 4-Trifluoromethyl-1H-pyrazol-5-ylamine; 4-(Trifluoromethyl)-5-aminopyrazole
EINECS	Contact for details

Quality Control

Our 4-(Trifluoromethyl)-1H-Pyrazol-5-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing purity (typically ≥95% to ≥98% by HPLC), residual solvents, and other critical parameters are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.