Description

(4R)-6,8-Dimethyl-3,4-Dihydro-2H-1-Benzopyran-4-Amine is a chiral amine derivative of a dihydrobenzopyran scaffold, serving as a valuable building block in advanced organic synthesis. This compound is critical for research and development in pharmaceutical chemistry, where its defined stereochemistry enables the creation of enantiomerically pure active ingredients. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for applications in asymmetric synthesis and medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of potential drug candidates, particularly in central nervous system (CNS) and cardiovascular research.
• Asymmetric Catalysis: Used as a ligand precursor or a chiral auxiliary in catalytic reactions to induce stereoselectivity.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and library synthesis for novel bioactive molecules.
• Agrochemical Development: Serves as a building block for creating chiral active ingredients with enhanced efficacy and environmental profile.
• Fine Chemical Synthesis: Utilized in the multi-step synthesis of complex natural products, flavors, and fragrances.
• Academic Research: A valuable compound for methodological studies in organic synthesis and stereochemistry at universities and research institutes.

Basic Information

Product Name	(4R)-6,8-Dimethyl-3,4-Dihydro-2H-1-Benzopyran-4-Amine
CAS No.	1055956-96-1
Molecular Formula	C11H15NO
Molecular Weight	177.24 g/mol
Synonyms	(4R)-6,8-Dimethyl-3,4-dihydro-2H-chromen-4-amine; (4R)-6,8-Dimethyl-3,4-dihydro-2H-1-benzopyran-4-amine; 2H-1-Benzopyran-4-amine, 3,4-dihydro-6,8-dimethyl-, (4R)-; (R)-6,8-Dimethyl-3,4-dihydro-2H-chromen-4-amine; 4-Amino-6,8-dimethylchroman; (4R)-4-Amino-6,8-dimethylchroman; 6,8-Dimethyl-3,4-dihydro-2H-1-benzopyran-4-amine (R-enantiomer)
EINECS	Contact for details

Quality Control

Our (4R)-6,8-Dimethyl-3,4-Dihydro-2H-1-Benzopyran-4-Amine is manufactured under strict quality control protocols to ensure high chemical and chiral purity for research and development applications. We provide comprehensive analytical data, including chiral HPLC for enantiomeric excess verification. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.