Description

(4R)-7-Fluoro-6-Methylchromane-4-Ylamine CAS NO 1055955-32-2 is a chiral chromane derivative, a high-purity advanced pharmaceutical intermediate (API) of significant importance in modern medicinal chemistry. Its value lies in its role as a critical building block for synthesizing novel, optically active therapeutic agents, particularly in central nervous system (CNS) and cardiovascular research. This compound is essential for pharmaceutical R&D departments and fine chemical manufacturers engaged in the development of new drug candidates requiring specific stereochemistry.

Application

• Key Intermediate in Pharmaceutical Synthesis: Serves as a crucial chiral precursor for the development of novel active pharmaceutical ingredients (APIs).
• Neurological & Psychiatric Drug Research: Used in the R&D of potential therapeutics targeting CNS disorders such as depression, anxiety, and neurodegenerative diseases.
• Cardiovascular Drug Development: Employed as a building block in the synthesis of compounds for cardiovascular disease research.
• Asymmetric Catalysis & Process Chemistry: Utilized in the development of stereoselective synthetic routes due to its defined (4R) configuration.
• Chemical Biology & Proteomics: Acts as a scaffold or modifier in the design of molecular probes for studying biological systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	(4R)-7-Fluoro-6-Methylchromane-4-Ylamine
CAS No.	1055955-32-2
Molecular Formula	C10H12FNO
Molecular Weight	181.21 g/mol
Synonyms	(4R)-7-Fluoro-6-methyl-3,4-dihydro-2H-chromen-4-amine; (4R)-7-Fluoro-6-methyl-2H-1-benzopyran-4-amine; 7-Fluoro-6-methylchromane-4-amine (R-enantiomer); (R)-7-Fluoro-6-methylchroman-4-amine; (4R)-7-Fluoro-6-methyl-3,4-dihydro-2H-1-benzopyran-4-amine; 4-Amino-7-fluoro-6-methylchroman (4R); (R)-4-Amino-7-fluoro-6-methylchroman
EINECS	Contact for details

Quality Control

Our (4R)-7-Fluoro-6-Methylchromane-4-Ylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric purity, to ensure compliance with exacting standards for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.